Integrin α2β1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates

Efforts to improve bone response to biomaterials have focused on ligands that bind α5β1 integrins. However, antibodies to α5β1 reduce osteoblast proliferation but do not affect differentiation when cells are grown on titanium (Ti). β1-silencing blocks the differentiation stimulus of Ti microtopograp...

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Detalhes bibliográficos
Main Authors: Olivares-Navarrete, R., Raz, P., Zhao, G., Chen, J., Wieland, M., Cochran, D. L., Chaudhri, R. A., Ornoy, A., Boyan, B. D., Schwartz, Z.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564982/
https://ncbi.nlm.nih.gov/pubmed/18843104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805420105
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