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Mutation screening of CHD5 in melanoma-prone families linked to 1p36 revealed no deleterious coding or splice site changes

BACKGROUND: A subset of cutaneous malignant melanoma and dysplastic nevi (CMM/DN) families is linked to 1p36. To date, no CMM/DN susceptibility gene has been identified at this locus. Data from mouse studies identified chromodomain helicase DNA binding protein 5 (CHD5) as a tumor suppressor affectin...

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Detalhes bibliográficos
Main Authors: Ng, David, Yang, Xiaohong R, Tucker, Margaret A, Goldstein, Alisa M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564952/
https://ncbi.nlm.nih.gov/pubmed/18803848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-1-86
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