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Cholesterol Interacts with Transmembrane α-helices M1, M3, and M4 of the Torpedo Nicotinic Acetylcholine Receptor: Photolabeling Studies using [(3)H]Azicholesterol

The photoactivatable sterol probe [3α-(3)H]6-Azi-5α-cholestan-3β-ol ([(3)H]Azicholesterol) was used to identify domains in the Torpedo californica nicotinic acetylcholine receptor (nAChR) that interact with cholesterol. [(3)H]Azicholesterol partitioned into nAChR-enriched membranes very efficiently...

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Detalhes bibliográficos
Main Authors: Hamouda, Ayman K., Chiara, David C., Sauls, Daniel, Cohen, Jonathan B., Blanton, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564873/
https://ncbi.nlm.nih.gov/pubmed/16411773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051978h
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