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Self-Assembly of HEK Cell-Secreted ApoE Particles Resemble ApoE-Enrichment of Lipoproteins as a Ligand for the LDL Receptor-Related Protein
Recent studies have shown that the lipidation and assembly state of apolipoprotein E (apoE) determine receptor recognition and amyloid-β peptide (Aβ) binding. We previously demonstrated that apoE secreted by HEK cells stably expressing apoE3 or apoE4 (HEK-apoE) binds Aβ, and inhibits Aβ-induced neur...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564845/ https://ncbi.nlm.nih.gov/pubmed/16401069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051765s |
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