Quality Control in the Secretory Pathway: The Role of Calreticulin, Calnexin and BiP in the Retention of Glycoproteins with C-Terminal Truncations

Unlike properly folded and assembled proteins, most misfolded and incompletely assembled proteins are retained in the endoplasmic reticulum of mammalian cells and degraded without transport to the Golgi complex. To analyze the mechanisms underlying this unique sorting process and its fidelity, the f...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Zhang, Jian-Xin, Braakman, Ineke, Matlack, Kent E.S., Helenius, Ari
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1997
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25647/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9348535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.10.1943
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