Quality Control in the Secretory Pathway: The Role of Calreticulin, Calnexin and BiP in the Retention of Glycoproteins with C-Terminal Truncations
Unlike properly folded and assembled proteins, most misfolded and incompletely assembled proteins are retained in the endoplasmic reticulum of mammalian cells and degraded without transport to the Golgi complex. To analyze the mechanisms underlying this unique sorting process and its fidelity, the f...
Uloženo v:
| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Cell Biology
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25647/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9348535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.10.1943 |
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