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Sequence variation in mitochondrial complex I genes: mutation or polymorphism?

BACKGROUND: Defects of the mitochondrial genome are recognised as common causes of genetic disease. Sequencing of large portions or even the entire mitochondrial genome is routine in many laboratories for the investigation of mitochondrial disease. However, establishing whether a detected sequence c...

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Sonraí Bibleagrafaíochta
Main Authors: Mitchell, A L, Elson, J L, Howell, N, Taylor, R W, Turnbull, D M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Group 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564640/
https://ncbi.nlm.nih.gov/pubmed/15972314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.032474
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