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Structural determinants of monohydroxylated bile acids to activate β(1) subunit-containing BK channels
Lithocholate (LC) (10–300 μM) in physiological solution is sensed by vascular myocyte large conductance, calcium- and voltage-gated potassium (BK) channel β(1) accessory subunits, leading to channel activation and arterial dilation. However, the structural features in steroid and target that determi...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563214/ https://ncbi.nlm.nih.gov/pubmed/18650555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800286-JLR200 |
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