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Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
The evolutionary-conserved interactions between KASH and SUN domain-containing proteins within the perinuclear space establish physical connections, called LINC complexes, between the nucleus and the cytoskeleton. Here, we show that the KASH domains of Nesprins 1, 2 and 3 interact promiscuously with...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562747/ https://ncbi.nlm.nih.gov/pubmed/18396275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.02.022 |
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