Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

The evolutionary-conserved interactions between KASH and SUN domain-containing proteins within the perinuclear space establish physical connections, called LINC complexes, between the nucleus and the cytoskeleton. Here, we show that the KASH domains of Nesprins 1, 2 and 3 interact promiscuously with...

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Bibliographic Details
Main Authors: Stewart-Hutchinson, P.J., Hale, Christopher M., Wirtz, Denis, Hodzic, Didier
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562747/
https://ncbi.nlm.nih.gov/pubmed/18396275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.02.022
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