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Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
The evolutionary-conserved interactions between KASH and SUN domain-containing proteins within the perinuclear space establish physical connections, called LINC complexes, between the nucleus and the cytoskeleton. Here, we show that the KASH domains of Nesprins 1, 2 and 3 interact promiscuously with...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562747/ https://ncbi.nlm.nih.gov/pubmed/18396275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.02.022 |
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