Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeys

To develop a live attenuated virus vaccine against St. Louis encephalitis virus (SLE), two antigenic chimeric viruses were generated by replacing the membrane precursor and envelope protein genes of dengue virus type 4 (DEN4) with those from SLE with or without a 30 nucleotide deletion in the DEN4 3...

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Bibliografiske detaljer
Main Authors: Blaney, Joseph E., Speicher, James, Hanson, Christopher T., Sathe, Neeraj S., Whitehead, Stephen S., Murphy, Brian R., Pletnev, Alexander G.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562685/
https://ncbi.nlm.nih.gov/pubmed/18586359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.05.075
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