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Cocaine Exposure In Vitro Induces Apoptosis in Fetal Locus Coeruleus Neurons by Altering the Bax/Bcl-2 Ratio and through Caspase-3 Apoptotic Signaling
Cocaine inhibits survival and growth of rat locus coeruleus (LC) neurons, which may mediate alterations in attention, following in utero exposure to cocaine. These effects are most severe in early gestation during peak neuritogenesis. Prenatal cocaine exposure may specifically decrease LC survival t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562674/ https://ncbi.nlm.nih.gov/pubmed/17084983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.04 |
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