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Amygdala BDNF signaling is required for consolidation but not encoding of extinction

Brain-derived neurotrophic factor (BDNF) acting through the tyrosine kinase B receptor (TrkB) is thought to be a critical mediator of learning. As there are no available selective antagonists of TrkB, we used a lentivirus encoding a dominant-negative TrkB (TrkB.t1) to antagonize BDNF signaling durin...

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Detalhes bibliográficos
Main Authors: Chhatwal, Jasmeer P, Stanek-Rattiner, Lisa, Davis, Michael, Ressler, Kerry J
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562628/
https://ncbi.nlm.nih.gov/pubmed/16783370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1718
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