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Seeding Neuritic Plaques from the Distance: A Possible Role for Brainstem Neurons in the Development of Alzheimer's Disease Pathology
BACKGROUND AND OBJECTIVE: Our goal is to obtain insight into the causes of the pathological lesions in Alzheimer's disease (AD). It is thought that the β-amyloid (Aβ) deposits within the cerebral cortex and hippocampus of AD brains are initiated by a ‘bad seed’ of oligomeric Aβ. The origin of t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562573/ https://ncbi.nlm.nih.gov/pubmed/18322404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113716 |
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