Bacteriophage T7 defective in the gene 6 exonuclease promotes site-specific cleavages of T7 DNA in vivo and in vitro.

Site-specific cleavages of intracellular DNA were demonstrated in bacteriophage T7 6am-infected cells. The sites of the cleavages were located at 46.8 and 68.7% (1% of the T7 DNA length = 400 base pairs) from the left end of the T7 genome. These cleavages required the products of genes 3 (endonuclea...

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Bibliographic Details
Published in:J Virol
Main Authors: Lee, D D, Sadowski, P D
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7143567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.44.1.235-240.1982
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