Formation of Kv2.1-FAK Complex as a Mechanism of FAK Activation, Cell Polarization and Enhanced Motility

Focal adhesion kinase (FAK) plays key roles in cell adhesion and migration. We now report that the delayed rectifier Kv2.1 potassium channel, through its LD-like motif in N-terminus, may interact with FAK and enhance phosphorylation of FAK(397) and FAK(576/577). Overlapping distribution of Kv2.1 and...

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Detalhes bibliográficos
Main Authors: Wei, Jian-feng, Wei, Ling, Zhou, Xin, Lu, Zhong-yang, Francis, Kevin, Hu, Xin-yang, Liu, Yu, Xiong, Wen-cheng, Zhang, Xiao, Banik, Naren L., Zheng, Shu-sen, Yu, Shan Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562431/
https://ncbi.nlm.nih.gov/pubmed/18615577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21530
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