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Design, Synthesis, and Biological Evaluation of Antiviral Agents Targeting Flavivirus Envelope Proteins

Flavivirus envelope proteins (E proteins) have been shown to play a pivotal role in virus assembly, morphogenesis, and infection of host cells. Inhibition of flavivirus infection of a host cell by means of a small molecule envelope protein antagonist is an attractive strategy for the development of...

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Detalhes bibliográficos
Main Authors: Li, Ze, Khaliq, Mansoora, Zhou, Zhigang, Post, Carol Beth, Kuhn, Richard J., Cushman, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562352/
https://ncbi.nlm.nih.gov/pubmed/18610998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800412d
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