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A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation

Methylation of histone 3 lysine 4 (H3K4) by yeast Set1-COMPASS requires prior monoubiquitination of histone H2B. To define whether other residues within the histones are also required for H3K4 methylation, we systematically generated a complete library of the alanine substitutions of all of the resi...

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Detalhes bibliográficos
Main Authors: Nakanishi, Shima, Sanderson, Brian W, Delventhal, Kym M, Bradford, William D, Staehling-Hampton, Karen, Shilatifard, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562305/
https://ncbi.nlm.nih.gov/pubmed/18622391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1454
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