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Effect of (+)-Methamphetamine on Path Integration Learning, Novel Object Recognition, and Neurotoxicity in Rats

RATIONALE: Methamphetamine (MA) has been implicated in cognitive deficits in humans after chronic use. Animal models of neurotoxic MA exposure reveal persistent damage to monoaminergic systems, but few associated cognitive effects. OBJECTIVES: Since, questions have been raised about the typical neur...

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Bibliographic Details
Main Authors: Herring, Nicole R., Schaefer, Tori L., Gudelsky, Gary A., Vorhees, Charles V., Williams, Michael T.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562284/
https://ncbi.nlm.nih.gov/pubmed/18509623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1183-y
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