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Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling

We have identified two genes, Smed-PTEN-1 and Smed-PTEN-2, capable of regulating stem cell function in the planarian Schmidtea mediterranea. Both genes encode proteins homologous to the mammalian tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN). Inactivation of Smed-P...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Oviedo, Néstor J., Pearson, Bret J., Levin, Michael, Sánchez Alvarado, Alejandro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Limited 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562200/
https://ncbi.nlm.nih.gov/pubmed/19048075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000117
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