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Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling
We have identified two genes, Smed-PTEN-1 and Smed-PTEN-2, capable of regulating stem cell function in the planarian Schmidtea mediterranea. Both genes encode proteins homologous to the mammalian tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN). Inactivation of Smed-P...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562200/ https://ncbi.nlm.nih.gov/pubmed/19048075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000117 |
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