Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2

The molecular basis for divalent cationic permeability in transient receptor potential melastatin subtype (TRPM) channels is not fully understood. Here we studied the roles of all eight acidic residues, glutamate or aspartate, and also the glutamine residue between pore helix and selectivity filter...

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Hlavní autoři: Xia, Rong, Mei, Zhu-Zhong, Mao, Hong-Ju, Yang, Wei, Dong, Li, Bradley, Helen, Beech, David J., Jiang, Lin-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562080/
https://ncbi.nlm.nih.gov/pubmed/18687688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801049200
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