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Imaging and Analysis of Transcription on Large, Surface-Mounted Single Template DNA Molecules

A surface-based approach is presented for the transcriptional analyses of large, single DNA molecule templates and their imaged reaction products by RNA polymerase (RNAP). Results showed surfaces with a charge density supporting stretching of single DNA molecules to 70–80% of their full contour leng...

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Detalhes bibliográficos
Main Authors: Yu, Hua, Schwartz, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561992/
https://ncbi.nlm.nih.gov/pubmed/18570883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.05.028
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