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DO THE PEPTIDE-BINDING PROPERTIES OF DIABETOGENIC CLASS II MOLECULES EXPLAIN AUTOREACTIVITY?

One seminal aspect in autoimmune diabetes is antigen presentation of beta cell antigens by the diabetes-propensity class II histocompatibility molecules. The binding properties of I-A(g7) molecules are reviewed here and an emphasis is placed on their selection of peptides with a highly specific sequ...

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Main Authors: Suri, Anish, Levisetti, Matteo G., Unanue, Emil R.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561945/
https://ncbi.nlm.nih.gov/pubmed/18082388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.10.007
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