Chargement en cours...
Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue
Many mutations that impact protein function occur at residues that do not directly contact ligand. To understand the functional contributions from the sequence that links the DNA-binding and regulatory domains of the LacI/GalR homologues, we have created a chimeric protein (LLhP), which comprises th...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561905/ https://ncbi.nlm.nih.gov/pubmed/18616293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800443k |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|