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Isolation and characterization of simian virus 40 early region deletion mutants.

We constructed a tsB4/dl884 double-mutant helper virus and used it to isolate two simian virus 40 early region deletion mutants that lack about half of the DNA sequences normally used to encode the large tumor antigen (T). Both mutants make a normal-sized small t antigen, but neither mutant can repl...

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Detalles Bibliográficos
Main Authors: Sompayrac, L M, Danna, K J
Formato: Artigo
Idioma:Inglês
Publicado: 1982
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC256124/
https://ncbi.nlm.nih.gov/pubmed/6287007
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