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Microglia Induce Neurotoxicity via Intraneuronal Zn(2+) Release and a K(+) Current Surge

Microglial cells are critical components of the injurious cascade in a large number of neurodegenerative diseases. However, the precise molecular mechanisms by which microglia mediate neuronal cell death have not been fully delineated. We report here that reactive species released from activated mic...

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Main Authors: KNOCH, MEGAN E., HARTNETT, KAREN A., HARA, HIROKAZU, KANDLER, KARL, AIZENMAN, ELIAS
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561170/
https://ncbi.nlm.nih.gov/pubmed/17955552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20592
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