Hemodynamics Influences Vascular Peroxynitrite Formation: Implication for LDL Apo B-100 Nitration

Hemodynamics, specifically, fluid shear stress, modulates the focal nature of atherogenesis. Superoxide anion (O(2)(−.)) reacts with nitric oxide ((.)NO) at a rapid diffusion-limited rate to form peroxynitrite (O(2)(−.) +(.)NO → ONOO(−)). Immunohistostaining of human coronary arterial bifurcations o...

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Autors principals: Hsiai, Tzung K., Hwang, Juliana, Barr, Mark L., Correa, Adria, Hamilton, Ryan, Alavi, Mohammad, Rouhanizadeh, Mahsa, Cadenas, Enrique, Hazen, Stanley L.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561143/
https://ncbi.nlm.nih.gov/pubmed/17275684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.11.017
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