Targeted Deletion of Neuropeptide Y (NPY) Modulates Experimental Colitis

BACKGROUND: Neurogenic inflammation plays a major role in the pathogenesis of inflammatory bowel disease (IBD). We examined the role of neuropeptide Y (NPY) and neuronal nitric oxide synthase (nNOS) in modulating colitis. METHODS: Colitis was induced by administration of dextran sodium sulphate (3%...

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Autori principali: Chandrasekharan, Bindu, Bala, Vanitha, Kolachala, Vasantha L., Vijay-Kumar, Matam, Jones, Dean, Gewirtz, Andrew T., Sitaraman, Shanthi V., Srinivasan, Shanthi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561053/
https://ncbi.nlm.nih.gov/pubmed/18836554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003304
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