Tumor necrosis factor (TNF)-neuropeptide Y (NPY) crosstalk regulates inflammation, epithelial barrier functions and colonic motility

BACKGROUND: Neuro-immune interactions play a significant role in regulating the severity of inflammation. Our previous work demonstrated that neuropeptide Y (NPY) is up regulated in the enteric nervous system (ENS) during murine colitis, and that NPY knockout mice exhibit reduced inflammation. Here...

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Autors principals: Chandrasekharan, Bindu, Jeppsson, Sabrina, Pienkowski, Stefan, Belsham, Denise D, Sitaraman, Shanthi V., Merlin, Didier, Kokkotou, Efi, Nusrat, Asma, Tansey, Malu G., Srinivasan, Shanthi
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180268/
https://ncbi.nlm.nih.gov/pubmed/24108115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.MIB.0000437042.59208.9f
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