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G-CSFR Ubiquitination Critically Regulates Myeloid Cell Survival and Proliferation
The granulocyte colony-stimulating factor receptor (G-CSFR) is a critical regulator of granulopoiesis. Mutations in the G-CSFR in patients with severe congenital neutropenia (SCN) transforming to acute myelogenous leukemia (AML) have been shown to induce hypersensitivity and enhanced growth response...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561048/ https://ncbi.nlm.nih.gov/pubmed/18923646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003422 |
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