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Mechanisms of Human Mitochondrial DNA Maintenance: The Determining Role of Primary Sequence and Length over Function

Although the regulation of mitochondrial DNA (mtDNA) copy number is performed by nuclear-coded factors, very little is known about the mechanisms controlling this process. We attempted to introduce nonhuman ape mtDNA into human cells harboring either no mtDNA or mutated mtDNAs (partial deletion and...

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Autori principali: Moraes, Carlos T., Kenyon, Lesley, Hao, Huiling
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25601/
https://ncbi.nlm.nih.gov/pubmed/10512871
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