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Plasmodium falciparum: Development of a Transgenic Line for Screening Antimalarials Using Firefly Luciferase as the Reporter
High-throughput screening (HTS) of small-molecule libraries against pharmacological targets is a key strategy of contemporary drug discovery. This study reports a simple, robust, and cell-based luminescent method for assaying antimalarial drugs. Using transfection technology, we generated a stable P...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2559859/ https://ncbi.nlm.nih.gov/pubmed/18579134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2008.05.003 |
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