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Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum

The recent reports of artemisinin (ART) resistance in the Thai-Cambodian border area raise a serious concern on the long-term efficacy of ARTs. To elucidate the resistance mechanisms, we performed in vitro selection with dihydroartemisinin (DHA) and obtained two parasite clones from Dd2 with more th...

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Bibliografiska uppgifter
Huvudupphovsmän: Cui, Long, Wang, Zenglei, Miao, Jun, Miao, Miao, Chandra, Ramesh, Jiang, Hongying, Su, Xin-zhuan, Cui, Liwang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455110/
https://ncbi.nlm.nih.gov/pubmed/22812578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08180.x
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