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Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum
The recent reports of artemisinin (ART) resistance in the Thai-Cambodian border area raise a serious concern on the long-term efficacy of ARTs. To elucidate the resistance mechanisms, we performed in vitro selection with dihydroartemisinin (DHA) and obtained two parasite clones from Dd2 with more th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455110/ https://ncbi.nlm.nih.gov/pubmed/22812578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08180.x |
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