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Sequences of herpes simplex virus type 1 that inhibit formation of stable TK+ transformants.

We have identified two regions of the herpes simplex virus type 1 (HSV-1) genome that inhibit DNA-mediated transformation of thymidine kinase-less L (Ltk-) cells by the cloned HSV-1 tk gene. When plasmids containing the EcoRI fragments EK or JK were mixed at 30 fmol/ml with the tk gene and transfect...

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Bibliographic Details
Published in:J Virol
Main Authors: Farkas, D H, Block, T M, Hart, P B, Hughes, R G
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255871/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3041018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.10.2989-2996.1987
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