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Demonstration in vitro that eucaryotic initiation factor 3 is active but that a cap-binding protein complex is inactive in poliovirus-infected HeLa cells.

Protein synthesis initiation factor preparations from poliovirus-infected HeLa cells have reduced ability to initiate translation on capped mRNA. The defect in initiation factors has been variously attributed to inactivation of eucaryotic initiation factor 3 (eIF3), eIF4B, or a cap-binding protein (...

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Publicado no:J Virol
Principais autores: Etchison, D, Hansen, J, Ehrenfeld, E, Edery, I, Sonenberg, N, Milburn, S, Hershey, J W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6088805/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.51.3.832-837.1984
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