Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.

Poliovirus infection of HeLa cells induces rapid shutoff of host protein synthesis, whereas translation of poliovirus RNA is not inhibited. It is presumed that shutoff is the result of proteolytic cleavage of component p220 of eucaryotic initiation factor 4F. To study whether poliovirus proteinase 2...

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Autores principales: Kräusslich, H G, Nicklin, M J, Toyoda, H, Etchison, D, Wimmer, E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC255777/
https://ncbi.nlm.nih.gov/pubmed/3039165
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