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Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function.

Transfection of a pBR322-based, recombinant plasmid, pAV2, containing the entire adeno-associated virus (AAV) type 2 genome into human 293 cells in the presence of helper adenovirus resulted in rescue and replication of AAV to yield infectious particles. We constructed mutants of pAV2 containing del...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Tratschin, J D, Miller, I L, Carter, B J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6088786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.51.3.611-619.1984
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