The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells.

A hybrid adeno-associated virus (AAV)/simian virus 40 (SV40) genome is described. In this construct SV40 regulatory sequences, including the early promoter/enhancers and origin of DNA replication, were substituted for the AAV p5 promoter, which normally controls expression of the AAV rep gene. The h...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Labow, M A, Berns, K I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2833621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.5.1705-1712.1988
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