The avian influenza virus nucleoprotein gene and a specific constellation of avian and human virus polymerase genes each specify attenuation of avian-human influenza A/Pintail/79 reassortant viruses for monkeys.

Reassortant viruses which possessed the hemagglutinin and neuraminidase genes of wild-type human influenza A viruses and the remaining six RNA segments (internal genes) of the avian A/Pintail/Alberta/119/79 (H4N6) virus were previously found to be attenuated in humans. To study the genetic basis of...

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Vydáno v:	J Virol
Hlavní autoři:	Snyder, M H, Buckler-White, A J, London, W T, Tierney, E L, Murphy, B R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1987
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2441080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.9.2857-2863.1987
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