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Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study

All molecular traffic between nucleus and cytoplasm occurs via the nuclear pore complex (NPC) within the nuclear envelope. In this study we analyzed the interactions of the nuclear transport receptors kapα2, kapβ1, kapβ1ΔN44, and kapβ2, and the model transport substrate, BSA-NLS, with NPCs to determ...

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Detalhes bibliográficos
Main Authors: Dange, Thomas, Grünwald, David, Grünwald, Antje, Peters, Reiner, Kubitscheck, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557044/
https://ncbi.nlm.nih.gov/pubmed/18824568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806173
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