Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration

BACKGROUND: The development of an immunocompetent, genetically modified mouse model to study HIV-1 pathogenesis and to test antiviral strategies has been hampered by the fact that cells from native mice do not or only inefficiently support several steps of the HIV-1 replication cycle. Upon HIV-1 inf...

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Bibliographic Details
Main Authors: Tervo, Hanna-Mari, Goffinet, Christine, Keppler, Oliver T
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557013/
https://ncbi.nlm.nih.gov/pubmed/18611257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-58
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