Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling

Tissue transglutaminase (TG2), an enzyme involved in protein cross-linking and overexpressed in ovarian tumors, has antiapoptotic effects in cancer cells and may play a role in response to chemotherapy. In this study, we investigated the role of TG2 in the sensitivity of ovarian cancer cells to cisp...

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Detaylı Bibliyografya
Asıl Yazarlar: Cao, Liyun, Petrusca, Daniela N., Satpathy, Minati, Nakshatri, Harikrishna, Petrache, Irina, Matei, Daniela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2008
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556973/
https://ncbi.nlm.nih.gov/pubmed/18667446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn158
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