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Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome.

Adenovirus type 5 deletion mutants that lack portions of their cis-acting DNA encapsidation signal synthesized nearly normal levels of viral DNA and late polypeptides but failed to efficiently package the DNA into virus particles. A series of mutant viruses carrying small deletions were produced and...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Hearing, P, Samulski, R J, Wishart, W L, Shenk, T
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1987
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3599182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.8.2555-2558.1987
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