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Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome.

Adenovirus type 5 deletion mutants that lack portions of their cis-acting DNA encapsidation signal synthesized nearly normal levels of viral DNA and late polypeptides but failed to efficiently package the DNA into virus particles. A series of mutant viruses carrying small deletions were produced and...

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Détails bibliographiques
Auteurs principaux: Hearing, P, Samulski, R J, Wishart, W L, Shenk, T
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC255695/
https://ncbi.nlm.nih.gov/pubmed/3599182
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