Transfectant Influenza A Viruses Are Effective Recombinant Immunogens in the Treatment of Experimental Cancer

Using reverse genetics methods, we constructed three different transfectant influenza A viruses encoding an L(d)-restricted, nine amino-acid-long fragment, corresponding to amino-acid residues 876–884, of β-galactosidase (β-gal). Sequences encoding this epitope were nested within the hemagglutinin (...

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Bibliographic Details
Main Authors: Restifo, Nicholas P., Surman, Deborah R., Zheng, Hongyong, Palese, Peter, Rosenberg, Steven A., García-Sastre, Adolfo
Format: Artigo
Language:Inglês
Published: 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556857/
https://ncbi.nlm.nih.gov/pubmed/9740780
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