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Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma

IL17-producing (Th17) cells are a distinct lineage of T helper cells that regulate immunity and inflammation. The role of antigen-presenting cells in the induction of Th17 cells in humans remains to be fully defined. Here, we show that human dendritic cells (DCs) are efficient inducers of Th17 cells...

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Detalhes bibliográficos
Main Authors: Dhodapkar, Kavita M., Barbuto, Scott, Matthews, Phillip, Kukreja, Anjli, Mazumder, Amitabha, Vesole, David, Jagannath, Sundar, Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556623/
https://ncbi.nlm.nih.gov/pubmed/18669891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143222
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