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Bortezomib enhances dendritic cell (DC)–mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications

Most anticancer chemotherapies are immunosuppressive and induce nonimmunogenic tumor cell death. Bortezomib, a specific inhibitor of 26S proteasome, has shown clinical activity in several human tumors, including myeloma. Here we show that the uptake of human myeloma cells by dendritic cells (DCs) af...

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Detaylı Bibliyografya
Asıl Yazarlar: Spisek, Radek, Charalambous, Anna, Mazumder, Amitabha, Vesole, David H., Jagannath, Sundar, Dhodapkar, Madhav V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885516/
https://ncbi.nlm.nih.gov/pubmed/17299090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-054221
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