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Simplified Synthetic TMC-95A/B Analogues Retain the Potency of Proteasome Inhibitory Activity
The proteasome regulates diverse intracellular processes, including cell-cycle progression, antigen presentation, and inflammatory response. Selective inhibitors of the proteasome have great therapeutic potential for the treatment of cancer and inflammatory disorders. Natural cyclic peptides TMC-95A...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556569/ https://ncbi.nlm.nih.gov/pubmed/12794861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200300560 |
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