Alterations of the Arginine Metabolome in Asthma

Rationale: As the sole nitrogen donor in nitric oxide (NO) synthesis and key intermediate in the urea cycle, arginine and its metabolic pathways are integrally linked to cellular respiration, metabolism, and inflammation. Objectives: We hypothesized that arginine (Arg) bioavailability would be assoc...

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Autori principali: Lara, Abigail, Khatri, Sumita B., Wang, Zeneng, Comhair, Suzy A. A., Xu, Weiling, Dweik, Raed A., Bodine, Melanie, Levison, Bruce S., Hammel, Jeffrey, Bleecker, Eugene, Busse, William, Calhoun, William J., Castro, Mario, Chung, Kian Fan, Curran-Everett, Douglas, Gaston, Benjamin, Israel, Elliot, Jarjour, Nizar, Moore, Wendy, Peters, Stephen P., Teague, W. Gerald, Wenzel, Sally, Hazen, Stanley L., Erzurum, Serpil C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2008
Soggetti:
A. Asthma and Allergy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556449/
https://ncbi.nlm.nih.gov/pubmed/18635886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200710-1542OC
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